Новое антибактериальнoе покрытие на основе смеси полиуретана с поли-L-лактидом

Abstract

Цель работы – экспериментальная проверка возможности ускорения диффузии антибактериального препарата из композиционного ПУ покрытия за счет введения в его состав добавки биодеградируемого ПЛ, а также определение влияния композиционных антибактериальных покрытий на формирование бактериальных пленок на поверхности титановых пластин. The introduction of a poly-L-lactide into an antibacterial coating based on the mixture of polyurethane, ciprofloxacin, and silver compounds prepared by the plasma-chemical synthesis is shown to accelerate the diffusion of antibacterial substances into the model environment Such acceleration is more likely due to the poly-L-lactide swelling in water, followed by a decrease in the energy of the intermolecular interaction between the polymer chains and an increase in a free coating volume A composition has been proposed of a four-component antibacterial nanocoating for titanium implants The coating proposed prevents the formation of bacterial films and has a profound antibacterial effect being stable under the abrasive medium action.